Babies fed with INFAT® OPO sleep more at night – thanks to newly discovered 7th health benefit

Infant formula companies using INFAT® can now differentiate their products with a unique and clinically proven- ‘Super Comfort’ positioning

Infant formula companies who include Advanced Lipid’s INFAT® OPO in their products can now use a compelling and scientifically-proven ‘Super Comfort’ marketing proposition in association with their brands.

A series of clinical trials have demonstrated that INFAT® OPO offers four separate benefits associated with baby’s comfort. This includes new preliminary evidence that infants fed with formula containing INFAT® OPO sleep for longer over the course of 24 hours and also during the night.

In total, this means INFAT® OPO has now been demonstrated to offer seven benefits, all of which are scientifically supported.

Four of these beneficial health effects are in the area of comfort, as follows:

  • Night sleep (the new 7th benefit) – A double-blind randomized controlled study involving 159 healthy term infants showed that infants fed formula containing INFAT® tend to enjoy more sleep at 6 weeks and 12 weeks than babies fed with control formula
  • Less crying – INFAT® is clinically proven to reduce crying time by up to 75% in healthy term babies – mainly in the late afternoon and evening – during the first weeks of their lives
  • Gut comfort – babies fed with formula containing INFAT® enjoy similar levels of beneficial gut bacteria to those found in breast-fed babies, promoting a healthy digestion and immune system
  • Softer stools – INFAT® promotes softer stools and in doing so reduces incidences of hard stools by as much as 50% compared with control formula

In addition to significantly greater levels of comfort, INFAT® optimizes the uptake of calcium, fat and energy. It has also been shown that bone strength in babies fed with INFAT® is similar to that found in breast-fed babies. Finally, bringing the list of benefits to seven, INFAT® has been shown to have a protective effect against gut inflammation, thereby enhancing gut health.
INFAT® OPO as an infant formula ingredient is unique in that it is a single ingredient that has been demonstrated to offer four comfort related benefits – something no other ingredient on the market can match. This means formula manufacturers can now market their products with a ‘Super Comfort’ positioning that will appeal to parents all over the world.

Avner Avissara, CEO of Advanced Lipids, commented: “Baby’s comfort is a high priority for parents of young babies, since it impacts on the whole family. An uncomfortable infant cries more and sleeps less – leading to stress and tiredness for parents. This means formula that promises increased comfort is an appealing proposition that resonates with mothers when they shop the baby aisle in-store. With INFAT® OPO, formula manufacturers can now use the Super-Comfort positioning to stand out on-shelf and gain a significant edge on their competitors.”

With INFAT® OPO it is now possible to create a formula with a fat composition that is closer than ever to breast milk in terms of structure and benefits. Breast milk is always best for baby, but when it isn’t possible to breast-feed, formula made with INFAT® OPO offers the next best solution, so parents can be confident they are giving their child a great start in life through optimum nutrition.

INFAT® OPO is an SN2 palmitate fat ingredient that when added as the fat component to infant formula mimics the composition and properties of human milk fat.

Produced in Europe using a patented enzymatic process, INFAT® delivers structured triglycerides with a high level of palmitic acid in the mid position of the triglyceride for optimal infant development and wellbeing. It is manufactured in state-of-the-art production facilities operated by AAK, which meet all of the most stringent European quality standards.


For more information, please contact:
Avner Avissara- CEO Advanced Lipids
tel:+ 972 54 6104700

Karel Stoschek- Chairman of the Board
tel: +46 709 422822

Ann Eshaw, Ingredient Communications
Tel: +44 141 280 4141

About Advanced Lipids

Advanced Lipids is a joint venture established by AAK, a global producer and supplier of speciality vegetable fats and oils for the infant formula industry, and Enzymotec, a leading biotech company specializing in lipid-based bio-functional ingredients. Combining Enzymotec’s clinical and chemical expertise in lipid technologies with AAK’s international strength in food safety, production and logistics, Advanced Lipids offers a unique package of clinical research, development, flexible blending, quality and logistics. Find out more at

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