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IMPROVED COMFORT

Babies nourished by formula conatinong INFAT exhibit less discomfort than those fed with regular breast milk substitutes.

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HEALTHY GROWTH

Infant formula containing INFAT ensures the developing baby receives proper nourishment for healthy growth.

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ENHANCED IMMUNITY

Clinical studies demonstrate that infant formula containing INFAT can help formula-fed babies acquire similar levels of beneficial gut bacteria as breastfed babies.

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Night sleep

Why do babies need to sleep? Sleep is a natural activity of the brain, and is especially important during early development, no less important than food, drink or safety. Human infants spend more time in sleep than in wakefulness during the first three years of their life, suggesting that sleep plays a more crucial role during this age period. Sleep directly impacts mental and physical development, and is vital to physical growth, the immune system, brain development, learning, memory, and more. Because a relaxed, well-fed infant can better get the sleep needed to grow and develop properly, nutrition plays an important role in enabling the comfort a baby requires to sleep well. INFAT® is a sn-2 palmitate fat ingredient which mimics the composition, structure and benefits of human milk fat. Infant formulas containing INFAT® promote proper digestion, leading to softer stools, less crying, and more sleep – altogether more comfort for the baby. INFAT® improves sleep in infants A double-blind, randomized controlled study involving 159 healthy term infants compared the sleep duration in the three days before the 6-week and 12-week visits of infants fed with infant formula containing INFAT®, standard formula (the control group), and breast milk. The results showed that the total duration of sleep in the INFAT group was higher compared to that in the control group both during night time, and across 24 hours. Download the Brochure Download the Article

Less crying

Why do babies cry? Crying is a basic, instinctive response. Most infants follow a universal crying pattern during the first few months of life. Often, crying is related to abdominal discomfort. This means that nutritional choices can have a major impact on a baby’s comfort and wellbeing. INFAT® is an sn-2 palmitate fat ingredient that mimics the composition, structure and benefits of human milk fat. Infant formulas containing INFAT promote proper digestion, leading to softer stools and much less crying – altogether more comfort for the baby. Download the Brochure INFAT_infographic_may 2016_LESS CRYING-Final-01

Softer stools

About stools and comfort An infant's stool can give an insight into its comfort and wellbeing. While a healthy, breastfed baby's stool is typically frequent, with a very runny consistency, a formula fed baby's stool is usually less frequent and more solid. Stool hardness can lead to pain and discomfort, and even to constipation. How does it work? Infant formulas with INFAT® are closer to mother's milk due to their high sn-2 palmitate fat structure, and have been clinically proven to benefit infants through better fat absorption and softer stools compared with control formulas with low sn-2 palmitate. Experts suggest that during the digestion process of the fat components in the intestine, palmitic acid that is not bound at the 2nd position and is released during digestion, tends to bind with calcium, and create calcium salts that are not well-absorbed. This impacts the infant's wellbeing in many ways: it can reduce absorption of fat needed for energy; it can lead to loss of calcium needed for healthy growth; and the calcium salts can cause harder stools, leading to discomfort. Download the Brochure

Bone Strength

Nutrition affects bone development Bones form the framework for a child’s growing body. They are living tissue that changes constantly, with old bone being replaced by new bone. Because it is widely believed that osteoporosis originates in childhood, researchers have made significant efforts to determine the factors that influence bone mineral buildup in healthy children. They found that the absorption of nutrients, such as minerals, fats, carbohydrates, and proteins, is tremendously important for normal infant growth and development and may contribute to early bone mineral buildup. This means that providing optimal nutrition during childhood may be essential to reaching the highest possible peak bone mass. INFAT® benefits bone strength parameters Studies show that INFAT® containing infant formula supports the absorption of calcuim and fat and strong and healthy bones. A clinical study carried out to compare the benefits of infant formula containing INFAT® with standard formula tested the formulas’ effects on infant's bone strength. It was demonstrated that term newborns fed with infant formula containing INFAT® for 12 weeks had a significantly higher bone speed of sound (SOS)* than that of newborns fed with standard infant formula. The bone SOS was comparable to that of breastfed term newborns. Download the Brochure Baby1

Fat & Calcium absorption

Helping babies grow: The link between fat, calcium abaorption and healthy growth Typically, babies triple their weight and double their height during their first year. Such rapid growth requires a high-fat diet, with frequent feedings and efficient fat and calcium absorption. By mimicking the qualities of human milk, infant formulas containing INFAT® increase fat absorption and improve calcium intake, for strong and healthy bones, and proper growth. Download the Brochure Baby2
 

Healthy gut bacteria

The importance of gut flora The intestinal microbiota, also known as the gut flora, is an essential organ that serves numerous important functions, including a continuous and dynamic effect on the immune system. Gut colonization begins after birth in a critical process that is heavily influenced by the newborn's nutrition. It is believed that human milk is an important factor in the initiation, development and composition of the gut flora. Human milk provides a source of microorgnisms such as lactic acid bacteria and bifidobacteria that are considered to be beneficial for human health. INFAT® containing infant formula was shown to support colonization of the gut with both lactobacilli and bifidobacteria. INFAT® containing infant formula increases levels of healthy gut bacteria A double blind, randomized controlled study on 36 term infants demonstrated that feeding with INFAT® formula for the first 6 weeks of life beneficially affected infant gut microbiota by increasing the lactobacillus and bifidobacteria counts in fecal stools compared to a control formula. This clinical study demonstrated that INFAT® may affect the intestinal microbiota composition during the first weeks of life. Colonization of the gut with lactobacillus and bifidobacteria are considered to be promoting good health, growth, and ability to fight off infections. A preclinical study revealed the potential protective role of INFAT® in a colitis mice model, showing that a low sn-2 palmitate diet increased intestinal damage while a high sn-2 palmitate diet limited the damage, though both diets contained the same palmitic acid content. This data suggests a crucial role for INFAT® in limiting intestinal inflammation. Download the Brochure Baby

Intestinal health

INFAT ® controls intestinal inflammation damage An animal knock out model for intestinal inflammation (Muc2 deficient mice), which is a well-described model of enterocolitis, was used to address the possible role of INFAT® on intestinal inflammation. Muc2 deficient mice (Muc2-/-) lack mucin2, which is a major component of the mucus layer that separates and provides a barrier for the intestinal epithelial cells from the intraluminal contents, and forms a physical barrier protecting the underlying epithelium against luminal substances and microbes . The deficiency of mucins in the Muc2-/- mice affects the protective capacities of the mucus layer, and as a consequence, bacteria are in direct contact with the intestinal epithelial cells. This in its turn leads to the development of spontaneous colitis in Muc2-/- mice. In this study mice fed diet with INFAT® demonstrated a lower extent of intestinal inflammatory damage compared with mice fed the control diet.